What Does Actavis promethazine codeine Mean?
What Does Actavis promethazine codeine Mean?
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Narcotic analgesics bring about histamine launch, which appears to get chargeable for wheals or urticaria occasionally seen at the positioning of injection on parenteral administration.
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Advise patients to normally use an precise milliliter measuring product when measuring and administering Promethazine HCl and Codeine Phosphate Oral Alternative. Inform people that a residence teaspoon will not be an precise measuring device and such use may lead to overdosage and really serious adverse reactions [see Overdosage (ten)].
Ensure that you not overfill the measuring gadget. This will likely assistance avert you from taking an excessive amount of medicine.
Daily life-threatening respiratory depression and Loss of life have happened in little ones who obtained codeine. Codeine is matter to variability in metabolism based mostly on CYP2D6 genotype (described below), which can cause a heightened exposure for the Energetic metabolite morphine. Based mostly upon post-promoting reviews, youngsters younger than twelve years old seem like extra susceptible to the respiratory depressant outcomes of codeine, specially if there are actually threat aspects for respiratory despair.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients under 6 decades of age, because the combination may possibly lead to fatal respiratory depression On this age populace. It can be crucial that promethazine hydrochloride and codeine phosphate syrup is measured with an exact measuring system (see Safeguards-Details for more info Sufferers).
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Opioid analgesics and antitussives, including codeine, among the list of Lively substances in Promethazine HCl and Codeine Phosphate Oral Alternative, get more info shouldn't be Utilized in clients with acute febrile disease affiliated with effective cough or in people with Serious respiratory disorder the place interference with power to obvious the tracheobronchial tree of secretions would have website a deleterious impact on the client’s respiratory functionality.
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苯丙胺 · 卡西酮 · 多巴胺 · 麻黃素 · 麦司卡林 · 甲基苯丙胺 · 苯乙胺 · 酪胺
The drug is excreted generally during the urine, mostly as inactive metabolites and modest quantities of cost-free and conjugated morphine. Negligible amounts of codeine and its metabolites are located in the feces.
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic check here hypotension）、小便不暢、便秘。
Promethazine and codeine may well bring about marked drowsiness or may perhaps impair the psychological and/or Actual physical abilities essential for that general performance of probably harmful responsibilities, which include driving a auto or functioning equipment.
This medicine may possibly comprise aspartame. Should you have phenylketonuria (PKU) or some other situation that needs you to limit your consumption of aspartame (or phenylalanine), talk to your medical doctor or pharmacist concerning the Harmless use of this medication.